Job details

• Independently design, plan and execute engineering strategies for Immune Cell Therapy discovery or technology projects. Delivers work on time and to budget.
• Maintain a high level of expertise in virology and gene editing technologies applied to immune cells and related assays through constant self-improvement utilising available training and maintains scientific knowledge through review of the scientific literature and conference attendance.
• Work as part of multi-disciplinary research drug discovery/technology project teams. Contribute to the development of clinical manufacture strategies, reagents or targets to support cell therapy discovery projects.
• Record and interpret complex experimental results and analyses and reports findings to manager, project teams and the wider organisation.
• Demonstrate scientific rigour in own data and that of others.
• Effectively present scientific results at internal meetings and participates, and may present, at external meetings.
• Provide training /guidance to junior scientists on technical and functional processes.
• Ensure that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards, e.g. Good Laboratory Practice (GLP).

• MSc or equivalent industry experience in Virology, Immunology, Immuno-Oncology
• Experience working with immune cells, such as T cells, CAR-Ts or other primary cells.
• Experience in creating and/or working with complex immunoassays including flow cytometry, cytokine assays, cytotoxicity assays.
• Hands on experience with cloning, production, and application of viral vectors such as Lentiviruses and Adeno-Associated Viruses (AAVs)
• Experience with gene editing tools such as CRISPR/Cas9, TALENs, Zinc fingers nucleases.
• Strong experimental design and problem-solving skills
• Scientific excellence as shown by previous work, publication history and references from scientific mentors.
• Excellent team working, communication and networking skills with experience of interacting effectively across interfaces of discipline, culture and expertise.

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